打开生物书的新方法:来听段有丝分裂rap!

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给有丝分裂来点节奏!来听一段生物rap吧:


视频来自:sciencemusicvideos


以下是歌词(以及大致的翻译_(:з」∠)_):


Interphase is cell division"s longest part,

间期是细胞分裂最长的部分

nuclear membrane"s intact as it starts,

它开始时核膜是完整的

The cell"s growing, cytoplasm flowing,

细胞生长,细胞质流动

chromosomes get duplicated, DNA gets replicated

染色体、DNA得以复制


Chromosomes are spread out so they can"t be seen distinctly

染色质散开,所以看不真切

But note the nucleolus, the ribosome factory

但看看核仁,这核糖体工厂

Outside the nucleus are two centrosomes,

外面是两个中心体

They later make a spindle which will pull apart the chromosomes.

它们稍后会形成纺锤丝,拽开染色体


Prophase follows, the chromosomes condense,

接下来是前期,缩成染色体

Each is made of two sister chromatids, (looks) like an "X"

每个都是一对姐妹单体,看起来像X

Each sister is a clone, the closest of kin,

每个姐妹都是克隆,最近的亲戚

And a centromere connects them like siamese twins,

着丝点连着它们,就像连体双胞胎


The nucleolus disappears it melts away,

核仁消失不见

as the cell takes a ribosome production holiday,

细胞放个核糖体生产假

the centrosomes separate, start spindle formation

中心体分开,形成纺锤体

for separating chromatids and cell elongation.

为了分开染色单体,让细胞伸长


CHORUS

Mitosis, chromosomal ride

有丝分裂,染色体的运动

Inter-, pro-, meta-, ana-, telophase, divide

间、前、中、后、末期,细胞分裂

Eukaryotes go from one cell to two,

真核生物一个细胞变俩

Mitosis, how cells renew.

有丝分裂,细胞就这样更新


In late prophase --prometaphase,

在前期的最后——前中期

The nuclear membrane disintegrates,

核膜瓦解

The centrosomes migrate to the cell"s opposing sides,

中心体移动到细胞的两端

And between them the fibers of the spindle wend and wind,

在它们之间纺锤丝延伸开


The spindle"s made of microtubule fibers which attach

纺锤由微管纤维构成,

to chromosomes at kinetochores, a protein patch

它通过着丝点连着染色体,

that serves like a handle that the fibers can grasp,

着丝点就像是这些纤维可以抓的把手

When they pull apart the chromosomes, splitting them in half,

拽着染色体,把它们分两半


The spindle moves the chromosomes with nudges so fine,

纺锤丝精细地移动染色体

Into linear formation on the 50 yard line

在50码线处排好队(注:50码线是美式足球场的正中间)

A location equatorial defining metaphase,

在赤道就位,这就定义了中期

where the chromosomes are lined up on that middle place

染色体们在中间位置排好


CHORUS


The spindle fibers pull on the kinetochores,

纺锤丝拽着着丝点

A cellular molecular mitotic tug of war,

细胞里的有丝分裂分子拔河

The centromere snaps, sisters get separated,

着丝粒断开,姐妹分离

Now these chromatids are chromosomes, they"ve been upgraded

现在这些染色单体升级成染色体啦


This snapping separation defines anaphase

这个分离定义了后期

The "A" for "apartness", for moving different ways,

A是分开的A,分道扬镳

Kinetochore spindle fibers separate the sisters

纺锤丝拽着着丝点分开姐妹

See "em waving goodbye, calling out "I"m gonna miss ya,"

看她们挥手告别,呼喊“我会想你的”


And the other spindle fibers push and grapple like felons

其他纺锤丝推动延伸

Makes the cell elliptical like a watermelon,

细胞像西瓜一样变成椭圆形

In telophase membranes form "round the chromosomes

在末期染色体周围形成膜

Which spread out as the nucleoli come on home

膜延伸开,核仁回来了


CHORUS


In animal cells there"s a ring of microfilaments

在动物细胞中有一圈微丝

that form at the equator and they cinch themselves in

在赤道形成收缩环,紧束自己

Tighter, tighter, tighter, tighter "til the cell is in two pieces,

紧点,紧点,再紧点,直到细胞一分两半

Yeah in animals, that"s cytokinesis

在动物细胞,这就是胞质分裂


But it"s different in plants in them the cell divides

但植物细胞方法不同

By building a new cell wall from the inside

它们在新细胞之间建一堵“ 墙 ”

As the Golgi sends vesicles with cellulosic goo,

高尔基体送来充满“纤维素胶”的囊泡


Which makes a plate, then a wall, divides the cell in two

它组成细胞板,把细胞一分为二


And instead of one mother cell we now have daughters two

现在一个母细胞变成了两个子细胞

Identical twins, kind of old but kind of new,

一模一样的双胞胎,既“新”又“旧”,

From your single celled beginning this is how you grew

从一个细胞开始,这就是你成长的方法

And for single celled eukaryotes it"s reproductive too!

而对单细胞真核生物,这也是繁殖!



题图来源:ThoughtCo

文章来源:本文经授权转载自作者本人公众号“酷炫科学”,转载请联系原账号。


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